SCHEMBL12889486

SCHEMBL12889486

Cc1cc(F)c(-c2cc(F)c(C(F)(F)Oc3cc(F)c(F)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12889566 1.00
SCHEMBL12889531 0.91
SCHEMBL14328302 0.91 RAPGEF4 (0.34)
SCHEMBL15603972 0.90 CYP11B1 (0.32)
SCHEMBL28667965 0.90 RAPGEF4 (0.35)
SCHEMBL12889554 0.89 ANPEP (0.33)
SCHEMBL15744599 0.88
SCHEMBL15744363 0.88
SCHEMBL12889590 0.88
SCHEMBL15603974 0.88 GPR3 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170166816-A1 PHOTOREACTIVE LIQUID CRYSTAL COMPOSITION, DISPLAY ELEMENT, OPTICAL ELEMENT, METHOD FOR MANUFACTURING DISPLAY ELEMENT, AND METHOD FOR MANUFACTURING OPTICAL ELEMENT UNIVERSITY OF HYOGO (JP) 2017-06-15 US disclosed
US-7888519-B2 Liquid crystals; using metastasis catalysts; reduction, hydrogenation MERCK PATENT GESELLSCHAFT (DE) 2011-02-15 US disclosed
US-7314943-B2 Pyran derivatives containing an exocyclic double bond MERCK PATENT GMBH (DE) 2008-01-01 US disclosed