Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.51 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.49 |
| ▸ | ITGAL | P20701 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12890386 | 1.00 | GHSR (0.51) | GHSRMAGI3ITGB2ICAM1ITGAL | |
| SCHEMBL12890377 | 0.84 | TACR1 (0.51) | GHSR | |
| SCHEMBL30311059 | 0.82 | ACE (0.64) | MAGI3 | |
| SCHEMBL13226652 | 0.80 | CAPN1 (0.54) | — | |
| SCHEMBL24122594 | 0.78 | ECE1 (0.69) | GHSRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL30493767 | 0.78 | ECE1 (0.69) | GHSRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL31729349 | 0.78 | GHSR (0.61) | GHSRMAGI3 | |
| SCHEMBL14864007 | 0.77 | ECE1 (0.57) | GHSRMAGI3 | |
| SCHEMBL21360941 | 0.76 | MAGI3 (0.70) | MAGI3KMT2A | |
| SCHEMBL20504633 | 0.76 | MAGI3 (0.70) | MAGI3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893223-B2 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING S.P.A. (IT) | 2011-02-22 | — | — | US | disclosed |