Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.70 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | CASP4 | P49662 | 1/20 | 0.57 |
| ▸ | CASP5 | P51878 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | CASP9 | P55211 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.57 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.57 |
| ▸ | EDNRA | P25101 | 1/20 | 0.57 |
| ▸ | ECE1 | P42892 | 5/20 | 0.54 |
| ▸ | MMP9 | P14780 | 7/20 | 0.50 |
| ▸ | MMP8 | P22894 | 7/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20504632 | 1.00 | MAGI3 (0.70) | MAGI3CASP1CASP3CASP4CASP5 | |
| SCHEMBL20504633 | 1.00 | MAGI3 (0.70) | MAGI3CASP1CASP3CASP4CASP5 | |
| SCHEMBL9069771 | 0.90 | MAGI3 (0.77) | MAGI3CASP1CASP3CASP4CASP5 | |
| SCHEMBL7400882 | 0.88 | EDNRA (0.71) | MAGI3CASP1CASP3CASP4CASP5 | |
| SCHEMBL7401288 | 0.87 | MAGI3 (0.64) | MAGI3CASP1CASP3CASP4CASP5 | |
| SCHEMBL7401285 | 0.87 | MAGI3 (0.64) | MAGI3CASP1CASP3CASP4CASP5 | |
| SCHEMBL7402345 | 0.86 | EDNRA (0.64) | MAGI3EDNRAECE1MMP9MMP8 | |
| SCHEMBL7402343 | 0.86 | EDNRA (0.64) | MAGI3EDNRAECE1MMP9MMP8 | |
| SCHEMBL9069770 | 0.85 | MAGI3 (0.68) | MAGI3CASP1CASP3CASP4CASP5 | |
| SCHEMBL7400880 | 0.84 | EDNRA (0.69) | MAGI3CASP1CASP3CASP4CASP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377515-B1 | GELATINASE INHIBITORS AND USE THEREOF | IPROTEOS S L (ES) | 2019-10-30 | — | — | EP | disclosed |
| US-10414797-B2 | Gelatinase inhibitors and use thereof | IPROTEOS S.L (ES) | 2019-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414797-B2 | Gelatinase inhibitors and use thereof | MMP8, SERPINE1, MMP9 | MAGI3 1277/4885CASP1 430/4885CASP3 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.