Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 7/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 7/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 7/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.34 |
| ▸ | RET | P07949 | 5/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12170621 | 0.84 | — | — | |
| SCHEMBL2665361 | 0.84 | LIMK1 (0.33) | RETLIMK1ADORA2AADORA1CDC7 | |
| SCHEMBL9942225 | 0.84 | HTT (0.34) | — | |
| SCHEMBL25057454 | 0.79 | PDPK1 (0.38) | RETCSF1R | |
| SCHEMBL12170619 | 0.79 | NUDT1 (0.35) | RETLMNA | |
| SCHEMBL19623260 | 0.79 | RET (0.31) | RET | |
| SCHEMBL19362553 | 0.74 | PRKD3 (0.36) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL12854738 | 0.74 | KDM4E (0.37) | PI4KAPI4K2BPI4K2API4KBMAP4K4 | |
| SCHEMBL24198438 | 0.70 | — | — | |
| SCHEMBL14621102 | 0.67 | NOS2 (0.54) | LIMK1TYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3430017-B1 | COMPOSITIONS AND METHODS FOR TREATING PARASITIC DISEASES | UNIV CALIFORNIA (US) | 2023-01-25 | — | — | EP | disclosed |
| EP-3153023-B1 | BENZOXAZOLE KINASE INHIBITORS AND METHODS OF USE | TAKEDA PHARMACEUTICALS CO (JP) | 2022-03-16 | — | — | EP | disclosed |
| WO-2017161344-A1 | COMPOSITIONS AND METHODS FOR TREATING PARASITIC DISEASES | THE REGANTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-09-21 | — | — | WO | disclosed |
| US-20150119351-A1 | THERAPY OF TUMORS AND INFECTIOUS AGENTS DEFICIENT IN METHYLTHIOADENOSINE PHOSPHORYLASE | LUBIN ADAM (US) | 2015-04-30 | — | — | US | disclosed |
| US-20110039868-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS, INC. (US) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039868-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | BTK, LCK, LYN | PI4KA 451/4885PI4K2B 390/4885PI4K2A 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.