Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.73 |
| ▸ | MAPT | P10636 | 9/20 | 0.73 |
| ▸ | MEN1 | O00255 | 6/20 | 0.73 |
| ▸ | LMNA | P02545 | 5/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.73 |
| ▸ | HTT | P42858 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | ASF1A | Q9Y294 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14535582 | 0.82 | KMT2A (0.70) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL6645832 | 0.82 | KDM4E (0.73) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL6645830 | 0.82 | KDM4E (0.73) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL30495458 | 0.79 | KMT2A (0.69) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL31393968 | 0.79 | KMT2A (0.74) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL17438107 | 0.79 | KMT2A (0.68) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL12316772 | 0.79 | KMT2A (0.68) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL13478299 | 0.78 | KMT2A (0.77) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL17438105 | 0.78 | KMT2A (0.77) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL20847078 | 0.78 | KDM4E (0.66) | KMT2AKDM4EMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893108-B2 | Antiviral methods and compositions | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-02-22 | — | — | US | disclosed |