Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.70 |
| ▸ | MAPT | P10636 | 9/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 9/20 | 0.60 |
| ▸ | LMNA | P02545 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | MITF | O75030 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | ASF1A | Q9Y294 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13478299 | 0.91 | KMT2A (0.77) | KMT2AKDM4EMAPTPOLBGAA | |
| SCHEMBL17438105 | 0.91 | KMT2A (0.77) | KMT2AKDM4EMAPTPOLBGAA | |
| SCHEMBL31393968 | 0.85 | KMT2A (0.74) | KMT2AKDM4EMAPTPOLBGAA | |
| SCHEMBL12892158 | 0.82 | KMT2A (0.73) | KMT2AKDM4EMAPTPOLBGAA | |
| SCHEMBL30310017 | 0.82 | KMT2A (1.00) | KMT2AKDM4EMAPTPOLBGAA | |
| Hydrochloric Acid SCHEMBL6641972 | 0.81 | KMT2A (0.97) | KMT2AKDM4EMAPTPOLBGAA | |
| Hydrochloric Acid SCHEMBL6641969 | 0.81 | KMT2A (0.97) | KMT2AKDM4EMAPTPOLBGAA | |
| SCHEMBL14195172 | 0.79 | KMT2A (0.78) | KMT2AKDM4EMAPTPOLBGAA | |
| SCHEMBL26974362 | 0.79 | PGR (0.76) | KMT2AKDM4EMAPTPOLBGAA | |
| SCHEMBL30495458 | 0.79 | KMT2A (0.69) | KMT2AKDM4EMAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007050673-A2 | CYCLIN DEPENDENT KINASE INHIBITORS | UNIVERSITY OF FLORIDA (US) | 2007-05-03 | — | — | WO | disclosed |