Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 8/20 | 0.74 |
| ▸ | MEN1 | O00255 | 8/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 9/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | MITF | O75030 | 3/20 | 0.66 |
| ▸ | ASF1A | Q9Y294 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | AR | P10275 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17438105 | 1.00 | KMT2A (0.77) | KMT2AKDM4EGAAMAPTMEN1 | |
| SCHEMBL14535582 | 0.91 | KMT2A (0.70) | KMT2AKDM4EGAAMAPTMEN1 | |
| SCHEMBL30310017 | 0.87 | KMT2A (1.00) | KMT2AKDM4EGAAMAPTMEN1 | |
| SCHEMBL31393968 | 0.87 | KMT2A (0.74) | KMT2AKDM4EGAAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL6641972 | 0.86 | KMT2A (0.97) | KMT2AKDM4EGAAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL6641969 | 0.86 | KMT2A (0.97) | KMT2AKDM4EGAAMAPTMEN1 | |
| SCHEMBL26974362 | 0.84 | PGR (0.76) | KMT2AKDM4EGAAMAPTMEN1 | |
| SCHEMBL14195172 | 0.84 | KMT2A (0.78) | KMT2AKDM4EGAAMAPTMEN1 | |
| SCHEMBL30495458 | 0.84 | KMT2A (0.69) | KMT2AKDM4EGAAMAPTMEN1 | |
| SCHEMBL9457623 | 0.83 | KMT2A (0.68) | KMT2AKDM4EGAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569356-B2 | Cyclin dependent kinase inhibitors | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569356-B2 | Cyclin dependent kinase inhibitors | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20100035940-A1 | Cyclin Dependent Kinase Inhibitors | UNIVERSITY OF FLORDIA RESEARCH FOUNDATION (US) | 2010-02-11 | — | — | US | disclosed |
| US-20100035940-A1 | Cyclin Dependent Kinase Inhibitors | UNIVERSITY OF FLORDIA RESEARCH FOUNDATION (US) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035940-A1 | Cyclin Dependent Kinase Inhibitors | CCNI, CCNK, CDK1 | KMT2A 1153/4885KDM4E 1029/4885GAA 2597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.