SCHEMBL12892255

SCHEMBL12892255

CSc1nccc(S)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12892253 0.77 ALOX15 (0.42)
SCHEMBL148439 0.76
SCHEMBL29987888 0.76
SCHEMBL5576942 0.74 ALDH1A1 (0.44)
SCHEMBL1131654 0.73
SCHEMBL104599 0.73
SCHEMBL29789628 0.73
SCHEMBL12453679 0.73
SCHEMBL29693610 0.73
SCHEMBL164463 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7880950-B2 low drive voltage, high display contrast, high reflectance and small variation of the reflectance of white display; exhibiting a decreased color change in white display after repeated driving operation of the display element KONICA MINOLTA HOLDINGS, INC. (JP) 2011-02-01 US disclosed
US-7880950-B2 low drive voltage, high display contrast, high reflectance and small variation of the reflectance of white display; exhibiting a decreased color change in white display after repeated driving operation of the display element KONICA MINOLTA HOLDINGS, INC. (JP) 2011-02-01 US disclosed
WO-2010135650-A1 N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-d]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS INCYTE CORPORATION (US) 2010-11-25 WO disclosed
US-7615562-B2 Such as 2-methyl-4-{5-[2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-thiophen-2-yl}-butan-2-ol; tumor necrosis factor inhibitors; immunosuppressants; antiinflammatory agents NOVARTIS AG (CH) 2009-11-10 US disclosed
US-20090243462-A1 DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2009-10-01 US disclosed
US-20090243462-A1 DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2009-10-01 US disclosed