Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620074 | 0.89 | POLB (0.66) | MMP13POLBHPGDHTTHDAC6 | |
| SCHEMBL14075729 | 0.85 | HDAC3 (0.60) | MMP13POLBHPGDHTTHDAC2 | |
| SCHEMBL764574 | 0.84 | MMP13 (0.81) | MMP13POLBHPGDHTTHDAC6 | |
| SCHEMBL23146039 | 0.83 | MMP13 (0.55) | MMP13POLBHPGDHTTHDAC6 | |
| Hydrochloric Acid SCHEMBL29090069 | 0.82 | MMP13 (0.78) | MMP13POLBHPGDHTTHDAC6 | |
| SCHEMBL8414232 | 0.82 | HDAC6 (0.53) | POLBHPGDHTTHDAC2HDAC8 | |
| SCHEMBL13366944 | 0.82 | MMP13 (0.54) | MMP13POLBHPGDHTTHDAC2 | |
| SCHEMBL8142775 | 0.82 | POLB (0.58) | MMP13POLBHPGDHTTHDAC2 | |
| SCHEMBL23471096 | 0.82 | POLB (0.58) | MMP13POLBHPGDHTTHDAC2 | |
| SCHEMBL12414159 | 0.81 | MMP13 (0.61) | MMP13POLBHPGDHTTPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091644-A2 | HSD17B13-RELATED DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-25 | — | — | WO | disclosed |
| US-7879953-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-02-01 | — | — | US | disclosed |