Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13052020 | 0.91 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTALDH1A1NFKB1KCNH2 | |
| SCHEMBL5506823 | 0.88 | SMN1; SMN2 (0.77) | SMN1; SMN2HTTALDH1A1NFKB1KCNH2 | |
| SCHEMBL13165401 | 0.87 | ALDH1A1 (0.63) | ALDH1A1POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL11719722 | 0.86 | SMN1; SMN2 (0.75) | SMN1; SMN2HTTALDH1A1NFKB1KCNH2 | |
| SCHEMBL11715301 | 0.86 | SMN1; SMN2 (0.75) | SMN1; SMN2HTTALDH1A1NFKB1KCNH2 | |
| SCHEMBL5502874 | 0.86 | SMN1; SMN2 (0.79) | SMN1; SMN2HTTALDH1A1NFKB1KCNH2 | |
| SCHEMBL22276926 | 0.85 | SMN1; SMN2 (0.63) | SMN1; SMN2HTTALDH1A1NFKB1KCNH2 | |
| SCHEMBL13052018 | 0.82 | ALDH1A1 (0.55) | SMN1; SMN2HTTALDH1A1NFKB1KCNH2 | |
| SCHEMBL15170741 | 0.82 | NPC1 (0.58) | ALDH1A1POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL9925387 | 0.82 | NPC1 (0.58) | ALDH1A1POLBHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879953-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-7786249-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-7772359-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-7632914-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2009-12-15 | — | — | US | disclosed |
| US-20090012606-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2009-01-08 | — | — | US | disclosed |
| US-20090012243-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2009-01-08 | — | — | US | disclosed |
| US-20090012259-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2009-01-08 | — | — | US | disclosed |
| US-7435788-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2008-10-14 | — | — | US | disclosed |