Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13199541 | 0.85 | MAPT (0.54) | ALDH1A1TP53HDAC1HDAC2CNR1 | |
| SCHEMBL13052020 | 0.83 | SMN1; SMN2 (0.56) | ALDH1A1TP53HIF1AHDAC1HDAC2 | |
| SCHEMBL12893243 | 0.82 | SMN1; SMN2 (0.66) | ALDH1A1TP53HIF1AHDAC1HDAC2 | |
| SCHEMBL14424475 | 0.77 | EPHX1 (0.64) | ALDH1A1HDAC1HDAC2CNR1HTT | |
| SCHEMBL20709030 | 0.76 | EPHX1 (0.77) | ALDH1A1HDAC1HDAC2HTTSMN1; SMN2 | |
| SCHEMBL24017724 | 0.75 | ALDH1A1 (0.59) | ALDH1A1TP53HIF1AHDAC1HDAC2 | |
| SCHEMBL12927922 | 0.74 | TSHR (0.55) | ALDH1A1CNR1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL14423986 | 0.74 | MAPT (0.76) | ALDH1A1TP53HIF1ACNR1HTT | |
| SCHEMBL16383171 | 0.74 | HTT (0.56) | ALDH1A1HDAC1HDAC2CNR1HTT | |
| SCHEMBL16378809 | 0.74 | CNR1 (0.53) | ALDH1A1TP53HIF1AHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297211-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2010-11-25 | — | — | US | disclosed |