SCHEMBL12893308

SCHEMBL12893308

CCOC(=O)c1ccnc(-c2cc(CC)ccn2)c1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
JMJD6 Q6NYC1 13/20 0.67
PIK3CA P42336 1/20 0.53
KDM4E B2RXH2 1/20 0.51
KDM6B O15054 1/20 0.51
KDM5C P41229 1/20 0.51
KDM4C Q9H3R0 1/20 0.51
KDM2A Q9Y2K7 1/20 0.51
KDM3A Q9Y4C1 1/20 0.51
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
CYP4F2 P78329 1/20 0.47
CYP4A11 Q02928 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30171421 0.92 JMJD6 (0.76) JMJD6PIK3CAKDM4EKDM6BKDM5C
SCHEMBL811785 0.92 JMJD6 (0.76) JMJD6PIK3CAKDM4EKDM6BKDM5C
SCHEMBL16139812 0.88 JMJD6 (0.57) JMJD6PIK3CAKDM4EKDM6BKDM5C
SCHEMBL12958351 0.88 JMJD6 (0.53) JMJD6PIK3CAKDM4ECA12CA1
SCHEMBL14616489 0.86 JMJD6 (0.55) JMJD6PIK3CACA12CA1CA2
SCHEMBL18121145 0.86 JMJD6 (0.68) JMJD6PIK3CAKDM4EKDM6BKDM5C
SCHEMBL17518777 0.86 KDM4E (0.69) JMJD6PIK3CAKDM4EKDM6BKDM5C
SCHEMBL2688111 0.86 JMJD6 (0.68) JMJD6PIK3CAKDM4EKDM6BKDM5C
SCHEMBL1333711 0.86 JMJD6 (0.68) JMJD6PIK3CAKDM4EKDM6BKDM5C
SCHEMBL28271627 0.86 KDM5C (0.69) JMJD6PIK3CAKDM4EKDM6BKDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8629269-B2 Dye for a dye-sensitised solar cell, and a solar cell comprising the same SOLARSYS CO., LTD. (KR) 2014-01-14 US disclosed
US-20110028716-A1 Dye for a Dye-Sensitised Solar Cell, and a Solar Cell Comprising the Same SOLARSYS CO., LTD. (KR) 2011-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028716-A1 Dye for a Dye-Sensitised Solar Cell, and a Solar Cell Comprising the Same DSG1, CRY1, DHODH JMJD6 3361/4885PIK3CA 2788/4885KDM4E 1162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.