Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.34 |
| ▸ | CD74 | P04233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4512403 | 0.86 | PDE10A (0.38) | SIRT6PRMT7PDE10ATACR3MAPT | |
| SCHEMBL12473398 | 0.83 | PDE10A (0.37) | SIRT6PRMT7PDE10ATACR3MAPT | |
| SCHEMBL12473432 | 0.81 | PDE10A (0.36) | SIRT6PRMT7PDE10ATACR3MAPT | |
| Hydrochloric Acid SCHEMBL4512248 | 0.80 | PDE10A (0.41) | SIRT6PDE10ATACR3MAPTALDH1A1 | |
| SCHEMBL12473409 | 0.79 | PDE10A (0.35) | SIRT6PRMT7PDE10ATACR3MAPT | |
| SCHEMBL12473350 | 0.78 | PDE10A (0.39) | SIRT6PDE10ATACR3MAPTALDH1A1 | |
| SCHEMBL12473359 | 0.77 | SIRT6 (0.36) | SIRT6PRMT7PDE10ATACR3MAPT | |
| Hydrochloric Acid SCHEMBL4493037 | 0.76 | PDE10A (0.38) | SIRT6PRMT7PDE10ATACR3MAPT | |
| SCHEMBL1289380 | 0.73 | MKNK1 (0.40) | SIRT6PDE10ATACR3MAPTALDH1A1 | |
| SCHEMBL12473319 | 0.73 | PRMT7 (0.35) | PRMT7MAPTALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |