Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.41 |
| ▸ | SCN1A | P35498 | 3/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27592145 | 0.78 | LTA4H (0.43) | HTR2ALMNATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL1289408 | 0.78 | TAAR1 (0.40) | TAAR1HTR2AHCAR2LMNAADRA2A | |
| SCHEMBL464725 | 0.76 | HCAR2 (0.45) | TAAR1HCAR2LMNAADRA2AADRA2B | |
| SCHEMBL27704702 | 0.76 | NPSR1 (0.39) | TAAR1HTR2AHCAR2LMNAADRA2A | |
| SCHEMBL10601685 | 0.74 | TSHR (0.43) | TAAR1TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27770216 | 0.73 | TSHR (0.41) | TAAR1LMNATSHRSLC6A2SLC6A4 | |
| SCHEMBL5431494 | 0.72 | HCAR2 (0.42) | TAAR1HCAR2LMNAADRA2AADRA2B | |
| SCHEMBL27685764 | 0.70 | HCAR2 (0.41) | TAAR1HCAR2LMNAADRA2AADRA2B | |
| SCHEMBL7853355 | 0.70 | HCAR2 (0.41) | TAAR1HCAR2LMNAADRA2AADRA2B | |
| Bicarbonate SCHEMBL6548895 | 0.69 | HCAR2 (0.53) | HCAR2LMNACYP2D6FFAR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621526-A1 | ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS | Agensys, Inc. (US) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012047724-A1 | ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS | AGENSYS, INC. (US) | 2012-04-12 | — | — | WO | disclosed |