Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 7/20 | 0.34 |
| ▸ | ACHE | P22303 | 7/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289508 | 0.82 | AGXT (0.41) | LOXL2AGXTBCHEACHEBACE1 | |
| SCHEMBL4498559 | 0.69 | APP (0.40) | BCHEACHEBACE1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4509842 | 0.67 | ITK (0.36) | LOXL2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16737085 | 0.66 | PLAU (0.42) | LOXL2BACE1MEN1KMT2AKDM4E | |
| SCHEMBL5776752 | 0.65 | LOXL2 (0.67) | LOXL2AGXTL3MBTL1SMN1; SMN2HTR2B | |
| SCHEMBL14075637 | 0.64 | LOXL2 (0.69) | LOXL2AGXTKDM4EHPGDL3MBTL1 | |
| SCHEMBL9826461 | 0.63 | LOXL2 (0.65) | LOXL2AGXTMAPTSMN1; SMN2HTR2B | |
| SCHEMBL7796043 | 0.62 | LOXL2 (0.62) | LOXL2AGXTMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL140395 | 0.61 | LOXL2 (0.71) | LOXL2AGXTSMN1; SMN2HTR2BHTR1A | |
| SCHEMBL7806512 | 0.61 | LOXL2 (0.60) | LOXL2AGXTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |