Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 7/20 | 0.33 |
| ▸ | ACHE | P22303 | 7/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289456 | 0.82 | LOXL2 (0.40) | AGXTLOXL2BCHEACHEBACE1 | |
| SCHEMBL4498559 | 0.69 | APP (0.40) | BCHEACHEBACE1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL4506936 | 0.68 | GPR55 (0.39) | BCHEACHEKDM4EMEN1ALDH1A1 | |
| SCHEMBL16737085 | 0.67 | PLAU (0.42) | LOXL2BACE1KDM4EMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4509842 | 0.65 | ITK (0.36) | LOXL2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL13530236 | 0.63 | AGXT (0.51) | AGXTLOXL2KDM4EALDH1A1MAPT | |
| SCHEMBL5776752 | 0.63 | LOXL2 (0.67) | AGXTLOXL2 | |
| SCHEMBL9826461 | 0.61 | LOXL2 (0.65) | AGXTLOXL2MAPT | |
| SCHEMBL1520921 | 0.61 | AGXT (1.00) | AGXTLOXL2KDM4ESLC6A4 | |
| SCHEMBL14145540 | 0.61 | AGXT (0.68) | AGXTLOXL2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |