Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.70 |
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | ACP1 | P24666 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4495246 | 0.99 | MAPK1 (0.68) | MAPK1TSHRALOX15TP53MAPT | |
| SCHEMBL1289434 | 0.82 | MAPK1 (0.71) | MAPK1TSHRALOX15TP53MAPT | |
| Hydrochloric Acid SCHEMBL4511251 | 0.81 | MAPK1 (0.70) | MAPK1TSHRALOX15TP53MAPT | |
| SCHEMBL1084021 | 0.79 | SMN1; SMN2 (0.79) | MAPK1TSHRALOX15TP53MAPT | |
| SCHEMBL4084663 | 0.78 | CYP1A2 (0.88) | MAPK1TSHRALOX15TP53MAPT | |
| SCHEMBL1289489 | 0.78 | ALDH1A1 (0.65) | MAPK1KMT2APOLBALDH1A1ACP1 | |
| SCHEMBL17695161 | 0.78 | KMT2A (1.00) | MAPK1TSHRALOX15TP53MAPT | |
| Hydrochloric Acid SCHEMBL4502066 | 0.77 | ALDH1A1 (0.67) | MAPK1KMT2APOLBALDH1A1ACP1 | |
| SCHEMBL1085597 | 0.76 | ACP1 (0.87) | MAPK1TSHRALOX15TP53MAPT | |
| SCHEMBL4920191 | 0.75 | ALOX15 (0.67) | MAPK1TSHRALOX15TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |