Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC8A1 | P32418 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1209119 | 0.91 | ALDH1A1 (0.40) | THRBMAPTLMNAMEN1KMT2A | |
| SCHEMBL12895691 | 0.90 | SLC8A1 (0.35) | SLC8A1THRBMAPTLMNATP53 | |
| SCHEMBL12895369 | 0.86 | SLC8A1 (0.34) | SLC8A1THRBMAPTLMNATP53 | |
| SCHEMBL12895524 | 0.84 | MAPT (0.35) | THRBMAPTLMNATP53RXFP1 | |
| SCHEMBL12895374 | 0.84 | THRB (0.35) | THRBMAPTLMNATP53RXFP1 | |
| SCHEMBL1210084 | 0.83 | ALDH1A1 (0.41) | THRBMAPTPOLBMEN1KMT2A | |
| SCHEMBL14293499 | 0.83 | MAPT (0.39) | THRBMAPTLMNAPOLBMEN1 | |
| SCHEMBL12895473 | 0.82 | MAPT (0.39) | THRBMAPTLMNATP53RXFP1 | |
| SCHEMBL1209436 | 0.82 | MAPT (0.41) | MAPTLMNATP53POLBMEN1 | |
| SCHEMBL1209698 | 0.81 | ALDH1A1 (0.40) | MAPTLMNATP53POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110044938-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | NYCOMED GMBH (DE) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110044938-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | BAX, BCL2, BAD | SLC8A1 4677/4885THRB 489/4885MAPT 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.