⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852646 | 0.78 | — | — | |
| SCHEMBL27292244 | 0.75 | — | — | |
| SCHEMBL7860768 | 0.74 | — | — | |
| SCHEMBL131555 | 0.73 | — | — | |
| SCHEMBL126993 | 0.73 | — | — | |
| SCHEMBL1289842 | 0.73 | — | — | |
| SCHEMBL28252018 | 0.71 | GPR84 (0.47) | — | |
| SCHEMBL131933 | 0.71 | — | — | |
| SCHEMBL1289796 | 0.71 | — | — | |
| SCHEMBL27450897 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153133-B1 | INJECTABLE PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | INTERVET INT BV (NL) | 2023-11-08 | — | — | EP | claimed |
| CN-110327468-A | Isoxazoline composition and its purposes in the parasitic infestation for preventing or treating animal | 英特维特国际股份有限公司 | 2019-10-15 | — | — | CN | claimed |
| CN-108685894-A | Soft chewing medicinal product | 英特维特国际股份有限公司 | 2018-10-23 | — | — | CN | claimed |
| CN-104203214-B | soft chewable pharmaceutical product | 英特维特国际股份有限公司 | 2018-05-25 | — | — | CN | claimed |
| CN-107750159-A | Drinking water for sterilization contains vitamin isoxazoline solution | 英特维特国际股份有限公司 | 2018-03-02 | — | — | CN | claimed |
| CN-106999475-A | Use of isoxazoline compounds for the treatment of demodex diseases | 英特维特国际股份有限公司 | 2017-08-01 | — | — | CN | claimed |
| CN-105992517-A | Antiparasitic use of isoxazoline compounds | 英特维特国际股份有限公司 | 2016-10-05 | — | — | CN | claimed |
| CN-105979944-A | Use of isoxazoline derivatives for treating or preventing arthropod infestations in poultry | 英特维特国际股份有限公司 | 2016-09-28 | — | — | CN | claimed |
| CN-105813651-A | Isoxazoline compositions and their use in preventing or treating parasitic infestations of animals | 英特维特国际股份有限公司 | 2016-07-27 | — | — | CN | claimed |
| CN-105616406-A | Topical localized isoxazoline formulation | INTERVET INT BV | 2016-06-01 | — | — | CN | claimed |
| CN-104780908-A | Manufacture of semi-plastic pharmaceutical dosage units | INTERVET INT BV | 2015-07-15 | — | — | CN | claimed |
| CN-104334159-A | Solid oral pharmaceutical compositions of isoxazoline compounds | INTERVET INT BV | 2015-02-04 | — | — | CN | claimed |
| CN-110327468-A | Isoxazoline composition and its purposes in the parasitic infestation for preventing or treating animal | 英特维特国际股份有限公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-109010296-A | The Solid oral pharmaceutical composition of isoxazoline compound | 英特维特国际股份有限公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-108685894-A | Soft chewing medicinal product | 英特维特国际股份有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108125951-A | Local external use's isoxazoline preparation comprising tetraethylene-glycol | 英特维特国际股份有限公司 | 2018-06-08 | — | — | CN | disclosed |
| EP-0232101-A2 | Light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1987-08-12 | — | — | EP | disclosed |
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |