Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18044696 | 0.89 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL1289794 | 0.83 | NOTUM (0.44) | POLBKDM4EALDH1A1AOC3LMNA | |
| SCHEMBL15878893 | 0.78 | KDM4E (0.45) | TSHRCHRNA7POLBKDM4EALDH1A1 | |
| SCHEMBL23146843 | 0.76 | POLB (0.52) | TSHRCHRNA7POLBKDM4EALDH1A1 | |
| SCHEMBL28341774 | 0.75 | MAPK1 (0.53) | CHRNA7POLBKDM4EALDH1A1HPGD | |
| SCHEMBL680979 | 0.74 | HPGD (0.56) | CHRNA7POLBKDM4EALDH1A1HPGD | |
| SCHEMBL21776526 | 0.74 | CHRNA7 (0.49) | CHRNA7POLBKDM4EALDH1A1HPGD | |
| SCHEMBL23147401 | 0.74 | CHRNA7 (0.49) | TSHRCHRNA7POLBKDM4EALDH1A1 | |
| SCHEMBL23147694 | 0.72 | GAA (0.46) | TSHRCHRNA7POLBKDM4EALDH1A1 | |
| SCHEMBL23617167 | 0.72 | KDM4E (0.47) | CHRNA7POLBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012045721-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2012-04-12 | — | — | WO | disclosed |