Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 5/20 | 0.41 |
| ▸ | SLC2A3 | P11169 | 4/20 | 0.41 |
| ▸ | SLC2A4 | P14672 | 3/20 | 0.41 |
| ▸ | SLC2A2 | P11168 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | USP14 | P54578 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1218252 | 0.81 | SLC2A1 (0.41) | CYP11B1CYP11B2KMT2ASLC2A1SLC2A3 | |
| SCHEMBL1217899 | 0.79 | CYP11B1 (0.46) | CYP11B1CYP11B2ARSLC2A1SLC2A3 | |
| SCHEMBL20534564 | 0.73 | KCNK13 (0.36) | CYP11B1CYP11B2TSHR | |
| SCHEMBL21120832 | 0.72 | ADORA2A (0.47) | KMT2AL3MBTL1 | |
| SCHEMBL16832421 | 0.70 | GAA (0.68) | CYP11B1CYP11B2ARKMT2ASLC2A1 | |
| SCHEMBL23161955 | 0.69 | KCNK13 (0.37) | CYP11B1CYP11B2 | |
| SCHEMBL3070156 | 0.69 | SLC2A1 (0.53) | CYP11B1CYP11B2ARSLC2A1SLC2A3 | |
| SCHEMBL18483017 | 0.69 | CYP2A6 (0.47) | CYP11B1CYP11B2ARTSHRCYP19A1 | |
| SCHEMBL3085330 | 0.69 | AR (0.50) | CYP11B1CYP11B2ARSLC2A1TSHR | |
| SCHEMBL18482888 | 0.68 | CYP11B1 (0.43) | CYP11B1CYP11B2ARTSHRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028447-A1 | INDAZOLE DERIVATIVES | PFIZER INC. | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028447-A1 | INDAZOLE DERIVATIVES | CNR1, CNR2, GPR119 | CYP11B1 149/4885CYP11B2 132/4885AR 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.