SCHEMBL1289883

SCHEMBL1289883

Cc1ccc(N(c2ccc(C)cc2)c2ccc(Nc3ccc(-c4ccc(Nc5ccc(N(c6ccc(C)cc6)c6ccc(C)cc6)cc5)c(-c5ccccc5)c4-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.44
NPC1 O15118 3/20 0.40
RAB9A P51151 2/20 0.40
MAPT P10636 6/20 0.38
GAA P10253 4/20 0.38
TDP1 Q9NUW8 1/20 0.38
CALCA P06881 1/20 0.37
TP53 P04637 3/20 0.36
ALDH1A1 P00352 1/20 0.35
LMNA P02545 3/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
KDM4E B2RXH2 2/20 0.35
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1289917 0.92 ALDH1A1 (0.34) HPGDNPC1RAB9AMAPTTDP1
SCHEMBL6131761 0.92 HPGD (0.52) HPGDNPC1RAB9AMAPTGAA
SCHEMBL29385958 0.89 NPSR1 (0.39) HPGDNPC1RAB9AMAPTGAA
SCHEMBL29353292 0.89 NPSR1 (0.39) HPGDNPC1RAB9AMAPTGAA
SCHEMBL15940007 0.89 NPSR1 (0.39) HPGDNPC1RAB9AMAPTGAA
SCHEMBL11907121 0.89 NPSR1 (0.39) HPGDNPC1RAB9AMAPTGAA
SCHEMBL30451170 0.89 ALDH1A1 (0.38) HPGDMAPTGAATDP1ALDH1A1
SCHEMBL7758598 0.89 HPGD (0.56) HPGDNPC1RAB9AMAPTGAA
SCHEMBL3638735 0.87 NPSR1 (0.42) HPGDMAPTGAAALDH1A1MEN1
SCHEMBL29402197 0.87 NPSR1 (0.42) HPGDMAPTGAAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2625171-A1 PHENANTHRO[9,10-B]FURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2013-08-14 EP disclosed
EP-2582770-A1 ORGANIC ELECTRONIC DEVICES COMPRISING THE LAYER CONTAINING AT LEAST ONE METAL ORGANIC COMPOUND AND AT LEAST ONE METAL OXIDE BASF SE (DE) 2013-04-24 EP disclosed
EP-2582769-A1 ORGANIC ELECTRONIC DEVICES COMPRISING A LAYER OF A DIBENZOFURANE COMPOUND AND A 8-HYDROXYQUINOLINOLATO EARTH ALKALINE METAL, OR ALKALI METAL COMPLEX BASF SE (DE) 2013-04-24 EP disclosed
WO-2012045710-A1 PHENANTHRO[9,10-B]FURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-04-12 WO disclosed
WO-2011157790-A1 ORGANIC ELECTRONIC DEVICES COMPRISING A LAYER OF A DIBENZOFURANE COMPOUND AND A 8-HYDROXYQUINOLINOLATO EARTH ALKALINE METAL, OR ALKALI METAL COMPLEX BASF SE (DE) 2011-12-22 WO disclosed
WO-2011158204-A1 ORGANIC ELECTRONIC DEVICES COMPRISING THE LAYER CONTAINING AT LEAST ONE METAL ORGANIC COMPOUND AND AT LEAST ONE METAL OXIDE BASF SE (DE) 2011-12-22 WO disclosed