SCHEMBL6131761

SCHEMBL6131761

Cc1ccc(Nc2ccc(-c3ccc(Nc4ccc(C)cc4)c(-c4ccccc4)c3-c3ccccc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.52
NPC1 O15118 4/20 0.46
RAB9A P51151 3/20 0.46
MAPT P10636 4/20 0.44
GAA P10253 4/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 4/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
TP53 P04637 3/20 0.39
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TUBB4A P04350 1/20 0.39
TUBB P07437 1/20 0.39
TUBA3C P0DPH7 1/20 0.39
TUBA1B P68363 1/20 0.39
TUBA4A P68366 1/20 0.39
TUBB4B P68371 1/20 0.39
TUBB3 Q13509 1/20 0.39
TUBB2A Q13885 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7758598 0.97 HPGD (0.56) HPGDNPC1RAB9AMAPTGAA
SCHEMBL5805392 0.94 HPGD (0.46) HPGDNPC1RAB9AMAPTGAA
SCHEMBL1289883 0.92 HPGD (0.44) HPGDNPC1RAB9AMAPTGAA
SCHEMBL31265542 0.89 ALDH1A1 (0.45) HPGDMAPTGAATDP1LMNA
SCHEMBL21838745 0.88 HPGD (0.59) HPGDNPC1RAB9AMAPTGAA
SCHEMBL530475 0.87 NPSR1 (0.57) HPGDMAPTGAAMEN1KMT2A
SCHEMBL29352577 0.87 NPSR1 (0.57) HPGDMAPTGAAMEN1KMT2A
SCHEMBL28016764 0.87 MAPT (0.44) HPGDNPC1RAB9AMAPTGAA
SCHEMBL29624616 0.87 FABP4 (0.49) HPGDNPC1RAB9AMAPTGAA
SCHEMBL29353544 0.85 NPSR1 (0.50) HPGDMAPTGAATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113755024-B Pure organic photosensitive dye with stepped energy transfer structure, and preparation method and application thereof 河南科技大学 2023-05-26 CN disclosed
US-6908638-B2 Organic electroluminescent element and method of manufacturing same MINOLTA CO., LTD. (JP) 2005-06-21 US disclosed
EP-1525629-A2 OPTOELECTRONIC DEVICES Qinetiq Limited (GB) 2005-04-27 EP disclosed
WO-2004013921-A2 OPTOELECTRONIC DEVICES QINETIQ LIMITED (GB) 2004-02-12 WO disclosed
EP-1186067-A1 CONDUCTING POLYMERS QinetiQ Limited (GB) 2002-03-13 EP disclosed
EP-1147563-A1 ORGANIC LIGHT EMITTING MATERIAL AND DEVICE QinetiQ Limited (GB) 2001-10-24 EP disclosed
WO-2000070692-A1 CONDUCTING POLYMERS QINETIQ LIMITED (GB) 2000-11-23 WO disclosed
WO-2000035029-A1 ORGANIC LIGHT EMITTING MATERIAL AND DEVICE THE SECRETARY OF STATE FOR DEFENCE (GB) 2000-06-15 WO disclosed