Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 2/20 | 0.47 |
| ▸ | MC5R | P33032 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3619110 | 0.93 | CYP1A2 (0.52) | CYP1A2CYP2A6HTR2AHTR2CHTR2B | |
| SCHEMBL131160 | 0.81 | CYP1A2 (0.56) | CYP1A2CYP2A6HTR2AHTR2CHTR2B | |
| SCHEMBL11719313 | 0.80 | CYP1A2 (0.60) | CYP1A2CYP2A6HTR2AHTR2CHTR2B | |
| SCHEMBL29774245 | 0.80 | CYP1A2 (0.60) | CYP1A2CYP2A6HTR2AHTR2CHTR2B | |
| SCHEMBL27548336 | 0.79 | ALDH1A1 (0.56) | CYP1A2CYP2A6RAB9A | |
| SCHEMBL2838141 | 0.79 | CYP1A2 (0.65) | CYP1A2CYP2A6HTR2AHTR2CHTR2B | |
| SCHEMBL6240981 | 0.79 | CYP1A2 (0.65) | CYP1A2CYP2A6HTR2AHTR2CHTR2B | |
| SCHEMBL29560700 | 0.79 | CYP1A2 (0.65) | CYP1A2CYP2A6HTR2AHTR2CHTR2B | |
| SCHEMBL131604 | 0.78 | CYP1A2 (0.62) | CYP1A2CYP2A6MC4RMC5RSIGMAR1 | |
| SCHEMBL15352007 | 0.76 | CYP2A6 (0.50) | CYP1A2CYP2A6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693573-A | Column arene bisphosphite ligand, and preparation method and application thereof | 北京旭阳科技有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-114460302-A | Biological probe and preparation method and application thereof | 深圳先进技术研究院 | 2022-05-10 | — | — | CN | claimed |
| CN-114441753-A | New coronavirus detection test strip and preparation method and application method thereof | 深圳先进技术研究院 | 2022-05-06 | — | — | CN | claimed |
| CN-114437157-A | Sialic acid Neu5Ac derivative and preparation method and application thereof | 深圳先进技术研究院 | 2022-05-06 | — | — | CN | claimed |
| CN-114181250-A | Alkenyl phosphine compound and preparation method thereof | 中国石油化工股份有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-106795117-B | Heterobicyclic compounds and their use for the treatment of tuberculosis | 大塚制药株式会社 | 2020-06-26 | — | — | CN | claimed |
| EP-3160977-A2 | BIPHENYL AMIDES WITH MODIFIED ETHER GROUPS AS HSP90 INHIBITORS AND HSP70 INDUCERS | The University of Kansas (US) | 2017-05-03 | — | — | EP | claimed |
| WO-2015200514-A2 | BIPHENYL AMIDES WITH MODIFIED ETHER GROUPS AS HSP90 INHIBITORS AND HSP70 INDUCERS | THE UNIVERSITY OF KANSAS (US) | 2015-12-30 | — | — | WO | claimed |
| US-8183383-B2 | Protein tyrosine phosphatase 1B inhibitor, preparation methods and uses thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2012-05-22 | — | — | US | claimed |
| US-RE42164-E1 | Hepatitis C inhibitor tri-peptides | BOEHRINGER INGELHEIM CANADA LTD. (CA) | 2011-02-22 | — | — | US | claimed |
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | claimed |
| US-5495018-A | ANTIBIOTIC INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1996-02-27 | — | — | US | claimed |
| US-5455271-A | Using aromatic amine derivitives as mosquito insecticide | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-10-03 | — | — | US | claimed |
| EP-0582810-A1 | Novel 7-(substituted)-8-(substituted)-9-(substituted amino)-6-demethyl-6-deoxyetracyclines as antibiotic agents | AMERICAN CYANAMID COMPANY (US) | 1994-02-16 | — | — | EP | claimed |
| WO-1994000420-A1 | NOVEL TIGHT-BINDING INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-06 | — | — | WO | claimed |
| EP-0351282-B1 | (1-Hydroxy-2-piperidinyl alkyl)-2-indolone, 2-quinolinones, 2-benzo[b]azepinone, 2-benzimidazolone and 2-quinazolinone derivatives, their preparation and therapeutical use | SYNTHELABO (FR) | 1993-10-27 | — | — | EP | claimed |
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | claimed |
| US-5034401-A | Cardiovascular disorders or antiischemia agents | SYNTHELABO (FR) | 1991-07-23 | — | — | US | claimed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | claimed |
| EP-0351282-A1 | (1-Hydroxy-2-piperidinyl alkyl)-2-indolone, 2-quinolinones, 2-benzo[b]azepinone, 2-benzimidazolone and 2-quinazolinone derivatives, their preparation and therapeutical use | SYNTHELABO (FR) | 1990-01-17 | — | — | EP | claimed |