Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.35 |
| ▸ | KDM4A | O75164 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.35 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isocitric Acid SCHEMBL27894954 | 1.00 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6TSHRGABRR1 | |
| Isocitric Acid SCHEMBL29645996 | 1.00 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6TSHRGABRR1 | |
| Isocitric Acid SCHEMBL30700829 | 1.00 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6TSHRGABRR1 | |
| Isocitric Acid SCHEMBL2794437 | 1.00 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6TSHRGABRR1 | |
| Isocitric Acid SCHEMBL6249818 | 1.00 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6TSHRGABRR1 | |
| Isocitric Acid SCHEMBL12927570 | 1.00 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6TSHRGABRR1 | |
| Isocitrate SCHEMBL8373 | 1.00 | TDP1 (0.68) | TDP1SMN1; SMN2SLC22A6TSHRGABRR1 | |
| Isocitrate SCHEMBL23648394 | 0.97 | TDP1 (0.65) | TDP1SMN1; SMN2SLC22A6TSHRGABRR1 | |
| Isocitrate SCHEMBL2580646 | 0.97 | TDP1 (0.74) | TDP1SMN1; SMN2SLC22A6TSHRGABRR1 | |
| Isocitrate SCHEMBL2396434 | 0.97 | TDP1 (0.65) | TDP1SMN1; SMN2SLC22A6TSHRGABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689144-A1 | CONSOLIDATED BIOPROCESSING OF COMPLEX CARBOHYDRATES TO D-erythro-ISOCITRIC ACID USING A FUNGUS | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie - Hans-Knöll-Institut - (DE) | 2026-02-11 | — | — | EP | disclosed |
| US-20260034177-A1 | HUMAN FUNCTIONAL CORNEAL ENDOTHELIAL CELL AND APPLICATION THEREOF | KYOTO PREFECTURAL PUBLIC UNIV CORP (JP) | 2026-02-05 | — | — | US | disclosed |
| WO-2024199940-A1 | CONSOLIDATED BIOPROCESSING OF COMPLEX CARBOHYDRATES TO D-erythro-ISOCITRIC ACID USING A FUNGUS | LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE – HANS-KNÖLL-INSTITUT – (DE) | 2024-10-03 | — | — | WO | disclosed |
| CN-118613596-A | Biomarkers for detecting and distinguishing invasive prostate cancer from inert forms and treatment of invasive prostate cancer | 约翰霍普金斯大学 | 2024-09-06 | — | — | CN | disclosed |
| US-20240164377-A1 | LOW VOLATILITY PROMOTING WATER CONDITIONING ADJUVANTS | ADJUVANTS UNLIMITED LLC (US) | 2024-05-23 | — | — | US | disclosed |
| CN-117571844-A | Method for detecting organic acid in human body tricarboxylic acid cycle | 凯莱谱科技股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| EP-4218773-A1 | HUMAN FUNCTIONAL CORNEAL ENDOTHELIAL CELL AND APPLICATION THEREOF | Kyoto Prefectural Public University Corporation (JP) | 2023-08-02 | — | — | EP | disclosed |
| CN-115267014-B | Method for detecting organic acid in tricarboxylic acid cycle | 杭州凯莱谱精准医疗检测技术有限公司 | 2023-05-26 | — | — | CN | disclosed |
| EP-3416658-B1 | HUMAN FUNCTIONAL CORNEAL ENDOTHELIAL CELL AND APPLICATION THEREOF | KYOTO PREFECTURAL PUBLIC UNIV CORP (JP) | 2023-03-22 | — | — | EP | disclosed |
| CN-115407065-A | Diagnostic and therapeutic preparations for thrombocytopenic multiple myeloma | 细胞生态海河实验室 | 2022-11-29 | — | — | CN | disclosed |
| CN-101793752-A | Isocitric acid determination reagent (kit) and isocitric acid concentration determination method | SUZHOU ANJ BIOTECH CO LTD | 2010-08-04 | — | — | CN | disclosed |
| CN-101609020-A | The method for measurement of concentration of isocitric acid measuring kit and isocitric acid | SUZHOU ANJ BIOTECH CO LTD (CN) | 2009-12-23 | — | — | CN | disclosed |
| CN-101609019-A | The method for measurement of concentration of isocitric acid measuring kit and isocitric acid | SUZHOU ANJ BIOTECH CO LTD (CN) | 2009-12-23 | — | — | CN | disclosed |
| CN-101464284-A | Isocitric acid measuring reagent kit and isocitric acid concentration determination method | SUZHOU ANJ BIOTECH CO LTD (CN) | 2009-06-24 | — | — | CN | disclosed |
| CN-101464308-A | Isocitric acid measuring reagent kit and isocitric acid concentration determination method | SUZHOU ANJ BIOTECH CO LTD (CN) | 2009-06-24 | — | — | CN | disclosed |
| CN-101464283-A | Isocitric acid measuring reagent kit and isocitric acid concentration determination method | SUZHOU ANJ BIOTECH CO LTD (CN) | 2009-06-24 | — | — | CN | disclosed |
| CN-101464282-A | Isocitric acid measuring reagent kit and isocitric acid concentration determination method | SUZHOU ANJ BIOTECH CO LTD (CN) | 2009-06-24 | — | — | CN | disclosed |
| CN-101464281-A | Isocitric acid measuring reagent kit and isocitric acid concentration determination method | SUZHOU ANJ BIOTECH CO LTD (CN) | 2009-06-24 | — | — | CN | disclosed |
| CN-101464285-A | Isocitric acid measuring reagent kit and isocitric acid concentration determination method | SUZHOU ANJ BIOTECH CO LTD (CN) | 2009-06-24 | — | — | CN | disclosed |
| US-4629690-A | COMPETITIVE PROTEIN BINDING USING A SECOND ENZYME RELATED TO THE FIRST BY THE PRODUCT OF ONE BEING THE SUBSTRATE OF THE OTHER | SYNTEX (U.S.A.) INC. (US) | 1986-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034177-A1 | HUMAN FUNCTIONAL CORNEAL ENDOTHELIAL CELL AND APPLICATION THEREOF | EPCAM, CD44, SLC17A5 | TDP1 4772/4885SMN1; SMN2 4697/4885SLC22A6 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.