Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967611 | 0.83 | — | — | |
| SCHEMBL22616333 | 0.81 | LMNA (0.38) | LMNASMN1; SMN2POLBKDM4EGAA | |
| SCHEMBL19114273 | 0.80 | LMNA (0.36) | LMNASMN1; SMN2POLBKDM4EGAA | |
| SCHEMBL15200246 | 0.80 | KDM4E (0.42) | LMNASMN1; SMN2POLBKDM4EGAA | |
| SCHEMBL24989267 | 0.79 | LMNA (0.37) | LMNASMN1; SMN2POLBKDM4EGAA | |
| SCHEMBL19457506 | 0.78 | MEN1 (0.41) | LMNAPOLBKDM4EGAAL3MBTL1 | |
| SCHEMBL5072771 | 0.78 | KDM4E (0.38) | LMNASMN1; SMN2POLBKDM4EGAA | |
| Methyl Alcohol SCHEMBL28096911 | 0.78 | CYP2D6 (0.39) | LMNASMN1; SMN2POLBKDM4EGAA | |
| SCHEMBL678153 | 0.77 | LMNA (0.40) | LMNASMN1; SMN2POLBKDM4EGAA | |
| SCHEMBL20763636 | 0.77 | LMNA (0.36) | LMNASMN1; SMN2POLBKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103124721-B | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide | DU PONT | 2015-06-03 | — | — | CN | disclosed |
| EP-2621894-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. Du Pont De Nemours And Company (US) | 2013-08-07 | — | — | EP | disclosed |
| CN-103124721-A | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide | DU PONT | 2013-05-29 | — | — | CN | disclosed |
| WO-2012047543-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-12 | — | — | WO | disclosed |