SCHEMBL678153

SCHEMBL678153

CNCC(=O)NCC(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
POLB P06746 2/20 0.39
KDM4E B2RXH2 4/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36
GAA P10253 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL677702 0.84 CA1 (0.34) CA1CA2
SCHEMBL22616333 0.81 LMNA (0.38) LMNAPOLBKDM4EL3MBTL1KMT2A
SCHEMBL15200246 0.80 KDM4E (0.42) LMNAPOLBKDM4EL3MBTL1KMT2A
SCHEMBL24989267 0.79 LMNA (0.37) LMNAPOLBKDM4EL3MBTL1KMT2A
SCHEMBL15715425 0.79 CA1 (0.36) CA1CA2
SCHEMBL19457506 0.78 MEN1 (0.41) LMNAPOLBKDM4EL3MBTL1KMT2A
SCHEMBL1289956 0.77 LMNA (0.40) LMNAPOLBKDM4EL3MBTL1KMT2A
SCHEMBL20763636 0.77 LMNA (0.36) LMNAPOLBKDM4EL3MBTL1KMT2A
SCHEMBL17081346 0.77 SMN1; SMN2 (0.37) LMNAPOLBKDM4EL3MBTL1KMT2A
SCHEMBL21764420 0.77 LMNA (0.37) LMNAPOLBKDM4EL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676535-A1 MULTI-ALBUMIN BINDING COMPOUNDS Ascendis Pharma A/S (DK) 2026-01-14 EP disclosed
WO-2024184354-A1 MULTI-ALBUMIN BINDING COMPOUNDS ASCENDIS PHARMA A/S (DK) 2024-09-12 WO disclosed
US-20140087943-A1 Pesticidal Active Mixtures Comprising Isoxazoline Compounds I BASF SE (DE) 2014-03-27 US disclosed
US-8563474-B2 Pestcidal active mixtures comprising isoxazoline compounds I BASF SE (DE) 2013-10-22 US disclosed
US-20110159107-A1 Pesticidal Mixtures Comprising Isoxazoline Compounds II BASF SE (DE) 2011-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110159107-A1 Pesticidal Mixtures Comprising Isoxazoline Compounds II PRDX1, PRDX2, PRDX5 LMNA 3855/4885POLB 4374/4885KDM4E 3212/4885
US-20140087943-A1 Pesticidal Active Mixtures Comprising Isoxazoline Compounds I CHRM3, CHRM5, CACNA1C LMNA 3451/4885POLB 4675/4885KDM4E 2282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.