SCHEMBL12899705

SCHEMBL12899705

CO[C@@H]1C(O)[C@H](C)O[C@@H]1C(O)CO

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
MANBA O00462 1/20 0.36
THRB P10828 1/20 0.36
HIF1A Q16665 1/20 0.36
CYP1A2 P05177 1/20 0.32
THPO P40225 1/20 0.32
SLC5A2 P31639 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12929267 1.00 LMNA (0.36) LMNAMANBATHRBHIF1ACYP1A2
SCHEMBL12930314 1.00 LMNA (0.36) LMNAMANBATHRBHIF1ACYP1A2
SCHEMBL12899706 1.00 LMNA (0.36) LMNAMANBATHRBHIF1ACYP1A2
SCHEMBL23603149 1.00 LMNA (0.36) LMNAMANBATHRBHIF1ACYP1A2
SCHEMBL17661516 1.00 LMNA (0.36) LMNAMANBATHRBHIF1ACYP1A2
SCHEMBL23603174 1.00 LMNA (0.36) LMNAMANBATHRBHIF1ACYP1A2
SCHEMBL23901028 0.84 MANBA (0.35) LMNAMANBATHRBHIF1ASLC5A2
SCHEMBL17657707 0.84 LMNA (0.37) LMNAMANBATHRBHIF1ACYP1A2
SCHEMBL19383250 0.84 LMNA (0.37) LMNAMANBATHRBHIF1ACYP1A2
SCHEMBL17657705 0.84 LMNA (0.37) LMNAMANBATHRBHIF1ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7884202-B2 Nucleobases are perfluoroalkylated in a one step process with a perfluoroalkyl halide in the presence of a sulfoxide, a peroxide and an iron compound; useful as medicinal drugs, intermediates for medicinal drugs and agricultural chemicals TOSOH CORPORATION (JP) 2011-02-08 US disclosed