Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MANBA | O00462 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17657705 | 1.00 | LMNA (0.37) | LMNAMANBATHRBHIF1ACYP1A2 | |
| SCHEMBL19383250 | 1.00 | LMNA (0.37) | LMNAMANBATHRBHIF1ACYP1A2 | |
| SCHEMBL10881344 | 0.85 | LMNA (0.37) | LMNAMANBATHRBHIF1ACYP1A2 | |
| SCHEMBL9490168 | 0.85 | LMNA (0.37) | LMNAMANBATHRBHIF1ACYP1A2 | |
| SCHEMBL10879734 | 0.85 | LMNA (0.37) | LMNAMANBATHRBHIF1ACYP1A2 | |
| SCHEMBL1269364 | 0.85 | LMNA (0.37) | LMNAMANBATHRBHIF1ACYP1A2 | |
| SCHEMBL23603149 | 0.84 | LMNA (0.36) | LMNAMANBATHRBHIF1ACYP1A2 | |
| SCHEMBL12899705 | 0.84 | LMNA (0.36) | LMNAMANBATHRBHIF1ACYP1A2 | |
| SCHEMBL17661516 | 0.84 | LMNA (0.36) | LMNAMANBATHRBHIF1ACYP1A2 | |
| SCHEMBL23603174 | 0.84 | LMNA (0.36) | LMNAMANBATHRBHIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469726-B2 | Water soluble polycarbonates for medical applications | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-10-18 | — | — | US | disclosed |
| US-9469726-B2 | Water soluble polycarbonates for medical applications | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-10-18 | — | — | US | disclosed |
| US-20160095933-A1 | WATER SOLUBLE POLYCARBONATES FOR MEDICAL APPLICATIONS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2016-04-07 | — | — | US | disclosed |
| US-20160095933-A1 | WATER SOLUBLE POLYCARBONATES FOR MEDICAL APPLICATIONS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160095933-A1 | WATER SOLUBLE POLYCARBONATES FOR MEDICAL APPLICATIONS | HGFAC, NONO, UACA | LMNA 4016/4885MANBA 3248/4885THRB 2955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.