SCHEMBL1290086

SCHEMBL1290086

NC(=O)CC[C@H](N)C(=O)O[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
KMT2A Q03164 1/20 0.38
USP2 O75604 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36
PDE4A P27815 1/20 0.34
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
DPP4 P27487 1/20 0.30
DPP8 Q6V1X1 1/20 0.30
DPP9 Q86TI2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3674990 0.86 USP2 (0.38) USP2SLCO1B1PDE4ALMNAL3MBTL1
SCHEMBL28983304 0.85 USP2 (0.42) USP2SLCO1B1PDE4ALMNAL3MBTL1
SCHEMBL16506171 0.85 USP2 (0.42) USP2SLCO1B1PDE4ALMNAL3MBTL1
SCHEMBL2525863 0.82 GSR (0.39) USP2SLCO1B1PDE4ADPP4DPP8
SCHEMBL1127060 0.81 ALOX15 (0.41) ALOX15BLMPMP22KMT2AUSP2
SCHEMBL5054613 0.81 USP2 (0.35) USP2SLCO1B1PDE4A
SCHEMBL736616 0.81 USP2 (0.39) USP2SLCO1B1PDE4ALMNAL3MBTL1
SCHEMBL14659366 0.81 USP2 (0.34) USP2SLCO1B1PDE4A
SCHEMBL3787584 0.81 USP2 (0.39) USP2SLCO1B1PDE4ALMNAL3MBTL1
SCHEMBL15145985 0.80 USP2 (0.41) USP2SLCO1B1PDE4ALMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116916950-A Compositions comprising Sbi adjuvants and methods of use thereof 螺旋纳米技术公司 2023-10-20 CN disclosed
US-11692184-B2 Thermostable RNA-guided endonucleases and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-04 US disclosed
CN-215799636-U Perfusion culture device for suspension cell ventilation bag 比欧联科供应链管理(北京)有限公司 2022-02-11 CN disclosed
US-20210324321-A9 CROSS-SCALE MODELING OF BIOREACTOR CULTURES USING RAMAN SPECTROSCOPY BIOGEN MA INC. (US) 2021-10-21 US disclosed
US-11118194-B2 Modified site-directed modifying polypeptides and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-09-14 US disclosed
US-20200392447-A1 CROSS-SCALE MODELING OF BIOREACTOR CULTURES USING RAMAN SPECTROSCOPY BIOGEN MA INC. (US) 2020-12-17 US disclosed
US-20200392472-A1 THERMOSTABLE RNA-GUIDED ENDONUCLEASES AND METHODS OF USE THEREOF NATIONAL SCIENCE FOUNDATION 2020-12-17 US disclosed
US-10563163-B2 Cross-scale modeling of bioreactor cultures using Raman spectroscopy BIOGEN MA INC. (US) 2020-02-18 US disclosed
WO-2019103984-A1 COMPOSITIONS INCLUDING FATP1, FATP3, FATP4, FATP5, AND/OR FATP6 INHIBITORS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2019-05-31 WO disclosed
US-10174065-B2 Antidiabetic enolic glucoside of phenylpyruvic acid ZADEC APS (DK) 2019-01-08 US disclosed
WO-1999007701-A1 TRICYCLIC QUINOXALINE DERIVATIVES AS PROTEIN TYROSINE KINASE INHIBITORS SUGEN, INC. (US) 1999-02-18 WO disclosed
WO-1998050356-A1 2-INDOLINONE DERIVATIVES AS MODULATORS OF PROTEIN KINASE ACTIVITY SUGEN, INC. (US) 1998-11-12 WO disclosed
US-5827729-A BLOOD DIALYSIS USING CULTURED LIVER TISSUE TO CLEANSE BLOOD WHICH FLOWS OVER ONE SIDE OF THE TISSUE WHILE NUTRIENTS FLOW OVER THE OTHER; DIFFUSION OF WASTES ADVANCED TISSUE SCIENCES (US) 1998-10-27 US disclosed
EP-0812210-A4 COMPOSITIONS AND METHODS FOR ENHANCING THE GROWTH OF HAIR AND RESTORING HAIR COLOR LIFE MEDICAL SCIENCES INC (US) 1998-08-19 EP disclosed
EP-0812210-A1 COMPOSITIONS AND METHODS FOR ENHANCING THE GROWTH OF HAIR AND RESTORING HAIR COLOR LIFE MEDICAL SCIENCES, INC. (US) 1997-12-17 EP disclosed
WO-1997039624-A1 DIFFUSION GRADIENT BIOREACTOR AND EXTRACORPOREAL LIVER DEVICE ADVANCED TISSUE SCIENCES, INC. (US) 1997-10-30 WO disclosed
WO-1996025943-A1 COMPOSITIONS AND METHODS FOR ENHANCING THE GROWTH OF HAIR AND RESTORING HAIR COLOR LIFE MEDICAL SCIENCES, INC. (US) 1996-08-29 WO disclosed
EP-0306607-A1 Vaccines for gram-negative bacteria MILES INC. (US) 1989-03-15 EP disclosed
US-4693891-A NONTOXIC, COUPLED PROTEIN, POLYSACCHARIDE AND LIPOPOLYSACCHARIDE MILES LABORATORIES, INC. (US) 1987-09-15 US disclosed
EP-0118831-A2 Vaccines for gram-negative bacteria and method for the preparation thereof MILES INC. (US) 1984-09-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10174065-B2 Antidiabetic enolic glucoside of phenylpyruvic acid PC, SLC5A1, SLC5A2 ALOX15 1819/4885BLM 4746/4885PMP22 1147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.