Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 8/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1232358 | 0.84 | MAPK10 (0.40) | CYP1A2ALDH1A1CYP3A4CYP2C19TAS2R14 | |
| SCHEMBL12900857 | 0.81 | NTRK1 (0.43) | CYP1A2ALDH1A1CYP3A4CYP2C19MAPK10 | |
| SCHEMBL12901052 | 0.81 | MEN1 (0.49) | CYP1A2ALDH1A1CYP3A4CYP2C19MAPK10 | |
| SCHEMBL12900855 | 0.76 | MAPK10 (0.45) | ALDH1A1MAPK10MAPK8MAPK9TSHR | |
| SCHEMBL12901794 | 0.75 | MAPK10 (0.38) | MAPK10MAPK8MAPK9KMT2ANPSR1 | |
| SCHEMBL12900858 | 0.75 | MAPK10 (0.48) | MAPK10MAPK8MAPK9DHODHHDAC6 | |
| SCHEMBL12900283 | 0.74 | MAPK10 (0.66) | MAPK10MAPK8MAPK9MAPK1 | |
| SCHEMBL12901775 | 0.74 | DHODH (0.35) | CYP1A2ALDH1A1MAPK10MAPK8NTRK1 | |
| SCHEMBL12900848 | 0.74 | SLC22A12 (0.47) | CYP1A2CYP3A4CYP2C19MAPK10MAPK8 | |
| SCHEMBL12901097 | 0.74 | MAPK10 (0.47) | MAPK10MAPK8MAPK9DHODHHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046121-A1 | INHIBITORS OF FOCAL ADHESION KINASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046121-A1 | INHIBITORS OF FOCAL ADHESION KINASE | PTK2, CABLES1, TNK2 | CYP1A2 4218/4885ALDH1A1 1557/4885CYP3A4 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.