Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ULK1 | O75385 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12901771 | 0.85 | MAPK10 (0.51) | MEN1KMT2AMAPK10GFERULK1 | |
| SCHEMBL1230847 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPK10GFERULK1 | |
| SCHEMBL12901776 | 0.81 | CYP1A2 (0.41) | MEN1KMT2AMAPK10ULK1MAPT | |
| SCHEMBL29689147 | 0.78 | MAPK10 (0.53) | MEN1KMT2AMAPK10GFERMAPT | |
| SCHEMBL16035800 | 0.78 | MAPK10 (0.53) | MEN1KMT2AMAPK10GFERMAPT | |
| SCHEMBL12901783 | 0.77 | NPC1 (0.50) | MAPTLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12901062 | 0.76 | KIF11 (0.50) | MAPK10CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL28688015 | 0.75 | MAPK10 (0.53) | MEN1KMT2AMAPK10GFERMAPT | |
| SCHEMBL12900855 | 0.73 | MAPK10 (0.45) | MAPK10TSHRALDH1A1MAPK9 | |
| SCHEMBL12900857 | 0.73 | NTRK1 (0.43) | MEN1KMT2AMAPK10ULK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046121-A1 | INHIBITORS OF FOCAL ADHESION KINASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046121-A1 | INHIBITORS OF FOCAL ADHESION KINASE | PTK2, CABLES1, TNK2 | MEN1 2909/4885KMT2A 1999/4885MAPK10 590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.