SCHEMBL12901972

SCHEMBL12901972

CN1CCOC2=C(c3c(P(c4ccccc4)c4ccccc4)ccc4c3OCCN4C)[C@H](P(c3ccccc3)c3ccccc3)CC=C21

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19021199 1.00 GRM5 (0.31) GRM5
SCHEMBL726239 0.79 GRM5 (0.39) GRM5
SCHEMBL30818349 0.79 GRM5 (0.39) GRM5
SCHEMBL15905925 0.76 GRM5 (0.36) GRM5
SCHEMBL22063024 0.73
SCHEMBL16449685 0.71 HTR1A (0.32)
SCHEMBL19912184 0.70 TNKS (0.34) GRM5
SCHEMBL19009978 0.70 GRM5 (0.33) GRM5
SCHEMBL14271036 0.69 HTR1A (0.32)
SCHEMBL14652965 0.69 HTR1A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7589196-B2 Amine-substituted biphenyldiphosphines SOLVIAS AG (CH) 2009-09-15 US disclosed