Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16808265 | 0.87 | ALDH1A1 (0.51) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL12909298 | 0.86 | STS (0.44) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL18504843 | 0.81 | MAOB (0.49) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL23623802 | 0.80 | CYP2C9 (0.45) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL12909280 | 0.79 | MEN1 (0.59) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL12909311 | 0.79 | CYP1A2 (0.43) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL12909312 | 0.78 | CYP2C9 (0.42) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL12909314 | 0.78 | CYP1A2 (0.42) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL15390246 | 0.78 | KMT2A (0.48) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL18947824 | 0.78 | KDM4E (0.47) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868147-B2 | substantially no fluorescent before the cleavage but highly fluorescent after the cleavage; traps a target substance such as an enzyme and emits fluorescence | Nagano, Tetsuo (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20080014602-A1 | Fluorescent Probe | SEKISUI MEDICAL CO., LTD. (JP) | 2008-01-17 | — | — | US | disclosed |