Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16808265 | 0.92 | ALDH1A1 (0.51) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL18504843 | 0.86 | MAOB (0.49) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL12909280 | 0.84 | MEN1 (0.59) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL12909298 | 0.83 | STS (0.44) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL15390246 | 0.83 | KMT2A (0.48) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL18947824 | 0.83 | KDM4E (0.47) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL12909311 | 0.82 | CYP1A2 (0.43) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL12909312 | 0.81 | CYP2C9 (0.42) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL12909314 | 0.81 | CYP1A2 (0.42) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 | |
| SCHEMBL12909299 | 0.80 | CYP2C9 (0.41) | CYP2C9CYP2C19CYP1A2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210207188-A1 | BETA-LACTAM COMPOUNDS AND METHODS OF USE THEREOF | THE UNIVERSITY OF HONG KONG (HK) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210207188-A1 | BETA-LACTAM COMPOUNDS AND METHODS OF USE THEREOF | MGAM, SI, PGLS | CYP2C9 510/4885CYP2C19 661/4885CYP1A2 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.