SCHEMBL12910327

SCHEMBL12910327

Cc1nc(-c2ccc(-c3[nH]c(C)nc3C)cc2)c(C)[nH]1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 3/20 0.55
▸ KDM4E B2RXH2 3/20 0.55
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ NPY5R Q15761 2/20 0.35
▸ ALDH1A1 P00352 2/20 0.33
▸ TGFBR1 P36897 4/20 0.33
▸ TGFBR2 P37173 2/20 0.33
▸ PTGS1 P23219 3/20 0.33
▸ PTGS2 P35354 3/20 0.33
▸ MAPK14 Q16539 2/20 0.32
▸ GSK3B P49841 1/20 0.32
▸ MAPK13 O15264 1/20 0.32
▸ GCGR P47871 1/20 0.32
▸ MAPK12 P53778 1/20 0.32
▸ MAPK11 Q15759 1/20 0.32
▸ HPGDS O60760 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22434857 0.80 KDM4E (0.47) HPGDKDM4ESMN1; SMN2NPY5RALDH1A1
SCHEMBL15676723 0.77 KDM4E (0.44) HPGDKDM4ESMN1; SMN2MAPK14GSK3B
SCHEMBL28019466 0.77 SMN1; SMN2 (0.44) HPGDKDM4ESMN1; SMN2NPY5RALDH1A1
SCHEMBL5204729 0.77 NPY5R (0.54) HPGDKDM4ESMN1; SMN2NPY5RALDH1A1
SCHEMBL17654426 0.77 SMN1; SMN2 (0.44) HPGDKDM4ESMN1; SMN2ALDH1A1MAPK14
SCHEMBL16713033 0.77 KDM4E (0.44) HPGDKDM4ESMN1; SMN2PTGS1PTGS2
SCHEMBL7601774 0.76 HPGD (0.68) HPGDKDM4ESMN1; SMN2NPY5RALDH1A1
SCHEMBL5850257 0.76 KDM4E (0.68) HPGDKDM4ESMN1; SMN2ALDH1A1LMNA
SCHEMBL949576 0.75 GSK3B (0.49) HPGDKDM4ESMN1; SMN2MAPK14GSK3B
SCHEMBL7041734 0.72 KDM4E (0.67) HPGDKDM4ESMN1; SMN2TGFBR1TGFBR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868064-B2 Ink receptive particles, material for recording, recording apparatus and ink receptive particle storage cartridge FUJI XEROX CO., LTD. (JP) 2011-01-11 — — US disclosed
US-7851518-B2 Ink receptive particles, material for recording, recording apparatus and ink receptive particle storage cartridge FUJI XEROX CO., LTD. (JP) 2010-12-14 — — US disclosed
US-20100045761-A1 INK RECEPTIVE PARTICLES, MATERIAL FOR RECORDING, RECORDING APPARATUS AND INK RECEPTIVE PARTICLE STORAGE CARTRIDGE FUJI XEROX CO., LTD. (JP) 2010-02-25 — — US disclosed
US-20100041812-A1 INK RECEPTIVE PARTICLES, MATERIAL FOR RECORDING, RECORDING APPARATUS AND INK RECEPTIVE PARTICLE STORAGE CARTRIDGE FUJI XEROX CO., LTD. (JP) 2010-02-18 — — US disclosed
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