Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.41 |
| ▸ | GCGR | P47871 | 4/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850257 | 0.81 | KDM4E (0.68) | KDM4EHPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL17654426 | 0.78 | SMN1; SMN2 (0.44) | KDM4EHPGDSMN1; SMN2MAPK14GCGR | |
| SCHEMBL1387860 | 0.76 | KDM4E (0.83) | KDM4EHPGDSMN1; SMN2MAPK14GCGR | |
| SCHEMBL9281941 | 0.76 | BRAF (0.47) | GSK3BCSNK1A1CSNK1DCLK2CSNK1G1 | |
| SCHEMBL12910327 | 0.75 | HPGD (0.55) | GSK3BKDM4EHPGDSMN1; SMN2MAPK14 | |
| SCHEMBL27335373 | 0.73 | MAPK14 (0.69) | GSK3BCSNK1A1CSNK1DKDM4EHPGD | |
| SCHEMBL9196324 | 0.73 | MAPK11 (0.69) | GSK3BCSNK1A1CSNK1DKDM4EHPGD | |
| SCHEMBL19868944 | 0.73 | MAPK14 (0.62) | GSK3BCSNK1A1CSNK1DKDM4EHPGD | |
| SCHEMBL19868943 | 0.71 | MAPK14 (0.67) | GSK3BKDM4ESMN1; SMN2MAPK14GCGR | |
| SCHEMBL24427789 | 0.71 | MKNK1 (0.46) | CSNK1DKDM4EHPGDSMN1; SMN2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-1564213-A1 | IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | HRH4, F2, HRH2 | GSK3B 2784/4885CSNK1A1 3129/4885CSNK1D 1468/4885 |
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | F2, H1-3, CYC1 | GSK3B 2365/4885CSNK1A1 3176/4885CSNK1D 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.