Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | GCGR | P47871 | 8/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.48 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204729 | 0.82 | NPY5R (0.54) | KDM4EHPGDSMN1; SMN2GCGRMAPK13 | |
| SCHEMBL6552000 | 0.82 | CNR1 (0.47) | KDM4EHPGDSMN1; SMN2GCGRMAPK14 | |
| SCHEMBL7046189 | 0.82 | HSD11B1 (0.47) | KDM4EHPGDSMN1; SMN2GCGRMAPK13 | |
| SCHEMBL5371873 | 0.81 | KDM4E (0.67) | KDM4EHPGDSMN1; SMN2GCGRMAPK13 | |
| SCHEMBL3956357 | 0.80 | MAPK13 (0.74) | GCGRMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL1068923 | 0.80 | KDM4E (1.00) | KDM4EHPGDSMN1; SMN2GCGRMAPK13 | |
| SCHEMBL9748575 | 0.78 | MAPK13 (0.83) | GCGRMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9749306 | 0.78 | HPGD (0.62) | KDM4EHPGDSMN1; SMN2GCGRMAPK13 | |
| SCHEMBL23437866 | 0.78 | MAPK13 (0.49) | KDM4EHPGDSMN1; SMN2GCGRMAPK13 | |
| SCHEMBL11514577 | 0.77 | KDM4E (0.67) | KDM4EHPGDSMN1; SMN2GCGRMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |