Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19330176 | 1.00 | TDP1 (0.59) | TDP1POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL19330148 | 0.84 | TDP1 (0.61) | TDP1POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL1291135 | 0.82 | POLB (0.59) | TDP1POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL30539297 | 0.74 | TDP1 (0.53) | TDP1POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL198490 | 0.74 | TDP1 (1.00) | TDP1POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL1905326 | 0.74 | TDP1 (0.53) | TDP1POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL29859234 | 0.74 | TDP1 (1.00) | TDP1POLBLMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10988320 | 0.73 | TDP1 (0.96) | TDP1POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL19330152 | 0.71 | ALDH1A1 (0.55) | TDP1POLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL19353921 | 0.71 | ERN1 (0.56) | POLBERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069514-B | Antibacterial compound and application thereof | 结核病药物开发全球联盟公司 | 2023-12-29 | — | — | CN | disclosed |