SCHEMBL12911702

SCHEMBL12911702

COC(=O)N(NC(=O)c1cc(Br)cc(Br)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl)C(C)=O

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.36
▸ PDE4B Q07343 4/20 0.34
▸ F10 P00742 4/20 0.33
▸ TRPV1 Q8NER1 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ OPRL1 P41146 1/20 0.31
▸ KLKB1 P03952 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13072527 0.96 DHODH (0.37) DHODHPDE4BF10TRPV1KDM4E
SCHEMBL12911699 0.94 DHODH (0.36) DHODHPDE4BF10TRPV1KDM4E
SCHEMBL13318569 0.90 DHODH (0.37) DHODHPDE4BF10TRPV1KDM4E
SCHEMBL12527874 0.90 DHODH (0.39) DHODHMEN1KMT2A
SCHEMBL12527873 0.89 KMT2A (0.38) DHODHF10MEN1KMT2A
SCHEMBL12911701 0.87 PDE4B (0.34) DHODHPDE4BF10TRPV1KDM4E
SCHEMBL13318571 0.86 DHODH (0.40) DHODHMEN1KMT2A
SCHEMBL10028769 0.86 CARM1 (0.39) DHODHPDE4BTRPV1KDM4EMEN1
SCHEMBL13072488 0.86 DHODH (0.37) DHODHPDE4BF10TRPV1KDM4E
SCHEMBL10028773 0.85 DHODH (0.37) DHODHPDE4BF10TRPV1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 — — US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT DHODH 284/4885PDE4B 275/4885F10 3713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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