SCHEMBL12911705

SCHEMBL12911705

CC(=O)NNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.41
▸ KMT2A Q03164 1/20 0.34
▸ PKM P14618 1/20 0.34
▸ PDE4A P27815 1/20 0.33
▸ PDE4B Q07343 1/20 0.33
▸ PDE4C Q08493 1/20 0.33
▸ PDE4D Q08499 1/20 0.33
▸ MALT1 Q9UDY8 1/20 0.33
▸ RIPK1 Q13546 2/20 0.32
▸ SLC2A1 P11166 2/20 0.32
▸ SLC2A3 P11169 2/20 0.32
▸ SLC2A4 P14672 2/20 0.32
▸ SLC2A2 P11168 1/20 0.32
▸ KCNH2 Q12809 4/20 0.32
▸ GCK P35557 3/20 0.32
▸ PPARG P37231 1/20 0.31
▸ JAK2 O60674 1/20 0.31
▸ JAK1 P23458 1/20 0.31
▸ TYK2 P29597 1/20 0.31
▸ JAK3 P52333 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13318577 0.92 DHODH (0.40) DHODHKMT2APKMPDE4APDE4B
SCHEMBL13073077 0.91 DHODH (0.40) DHODHKMT2APKMPDE4APDE4B
Cyantraniliprole SCHEMBL29354965 0.91 DHODH (0.42) DHODHKMT2APKMPDE4APDE4B
Cyantraniliprole SCHEMBL166640 0.91 DHODH (0.42) DHODHKMT2APKMPDE4APDE4B
SCHEMBL20262070 0.91 DHODH (0.42) DHODHKMT2APKMPDE4APDE4B
SCHEMBL12559348 0.90 DHODH (0.40) DHODHKMT2APKMPDE4APDE4B
SCHEMBL950199 0.90 DHODH (0.42) DHODHKMT2APKMPDE4APDE4B
SCHEMBL24101462 0.90 DHODH (0.43) DHODHKMT2APKMPDE4APDE4B
SCHEMBL15271704 0.90 DHODH (0.43) DHODHKMT2APKMPDE4APDE4B
SCHEMBL12911576 0.90 DHODH (0.43) DHODHKMT2AMALT1RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 — — US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT DHODH 284/4885KMT2A 1294/4885PKM 600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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