SCHEMBL950199

SCHEMBL950199

Cc1cc(C#N)cc(C(=O)NN)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.42
SLC2A1 P11166 3/20 0.35
SLC2A3 P11169 3/20 0.35
SLC2A4 P14672 3/20 0.35
SLC2A2 P11168 1/20 0.35
KMT2A Q03164 2/20 0.35
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
PKM P14618 1/20 0.35
P2RX7 Q99572 1/20 0.34
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
KCNH2 Q12809 5/20 0.34
GCK P35557 4/20 0.34
MALT1 Q9UDY8 1/20 0.33
PPARG P37231 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28867332 0.93 DHODH (0.43) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL31059983 0.92 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL29377007 0.92 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
Cyantraniliprole SCHEMBL166640 0.92 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL959387 0.92 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
Cyantraniliprole SCHEMBL29354965 0.92 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL14524810 0.92 DHODH (0.41) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL11893154 0.92 DHODH (0.41) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL24101462 0.91 DHODH (0.43) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL15271704 0.91 DHODH (0.43) DHODHSLC2A1SLC2A3SLC2A4SLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 US disclosed
EP-1937664-B1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2011-06-15 EP disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 US disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 EP disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 EP disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 US disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 DHODH 771/4885SLC2A1 1654/4885SLC2A3 1853/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT DHODH 284/4885SLC2A1 909/4885SLC2A3 1051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.