Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14455169 | 0.87 | MAPT (0.52) | MAPTRAB9ANPC1LMNACHRM1 | |
| SCHEMBL31106542 | 0.86 | CDK5 (0.58) | MAPTRAB9ANPC1LMNAIDO1 | |
| SCHEMBL19107709 | 0.82 | CHRM1 (0.53) | MAPTRAB9ANPC1LMNAIDO1 | |
| SCHEMBL12316864 | 0.81 | MAPT (0.87) | MAPTRAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL10470932 | 0.80 | CHRM1 (0.51) | MAPTRAB9ANPC1LMNAIDO1 | |
| SCHEMBL28253943 | 0.77 | MAPT (0.43) | MAPTRAB9ANPC1LMNAIDO1 | |
| SCHEMBL11653909 | 0.76 | CHRM1 (0.48) | MAPTRAB9ANPC1LMNAIDO1 | |
| SCHEMBL29706122 | 0.76 | RXRA (0.48) | MAPTRAB9ANPC1LMNAIDO1 | |
| SCHEMBL29706181 | 0.76 | RARB (0.48) | MAPTRAB9ANPC1IDO1SMN1; SMN2 | |
| SCHEMBL12912867 | 0.76 | IDO1 (0.50) | MAPTRAB9ANPC1LMNAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420750-B2 | Copolymers of dibendiazocine with difunctional monomers containing sulfone and/or ketone units | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20110009563-A1 | Copolymers of dibendiazocine with difunctional monomers containing sulfone and/or ketone units | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-01-13 | — | — | US | disclosed |
| US-7238771-B2 | Dibenzodiazocine polymers | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2007-07-03 | — | — | US | disclosed |