Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CCKBR | P32239 | 7/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29706122 | 0.86 | RXRA (0.48) | RARBMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL29706128 | 0.85 | CCKBR (0.53) | RARBMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL29706233 | 0.84 | OPRK1 (0.48) | RARBMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL30962460 | 0.79 | TERT (0.39) | RARBMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL12912968 | 0.76 | MAPT (0.58) | MAPTKMT2ASMN1; SMN2TDP1GSK3A | |
| SCHEMBL19631021 | 0.75 | RARB (0.75) | RARBMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL29706125 | 0.73 | OPRK1 (0.57) | RARBGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10370989 | 0.71 | CCKBR (0.46) | RARBMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL29706177 | 0.71 | RXRA (0.48) | RARBMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL29706210 | 0.71 | RXRA (0.46) | RARBMAPTMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702454-A | Preparation method of 5-alkyl-11-aryl-5H-dibenzo [ b, e ] [1,4] diazepine derivative | 江西师范大学 | 2022-07-05 | — | — | CN | disclosed |