Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4B | O94953 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PDE8A | O60658 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12782242 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KDM4ETDP1POLBMETAP2 | |
| SCHEMBL12912973 | 0.92 | KDM5C (0.45) | MEN1KMT2AKDM5CKDM4CCXCR4 | |
| SCHEMBL940224 | 0.85 | CXCR4 (0.50) | ALDH1A1KDM4EPOLBMETAP2SMN1; SMN2 | |
| SCHEMBL24092361 | 0.84 | KDM4E (0.45) | ALDH1A1KDM4ETDP1METAP2MC4R | |
| SCHEMBL18390905 | 0.82 | CCR1 (0.47) | KDM4EMETAP2MC4RLMNAHRH4 | |
| SCHEMBL12946190 | 0.81 | KDM4E (0.43) | KDM4ETDP1METAP2MC4RKMT2A | |
| SCHEMBL3396399 | 0.81 | LMNA (0.51) | KDM4EMETAP2MC4RKMT2ALMNA | |
| SCHEMBL5117431 | 0.81 | CYP2A13 (0.54) | KDM4EMETAP2CXCR4 | |
| SCHEMBL18320625 | 0.79 | CHKA (0.48) | ALDH1A1KDM4ETDP1POLBCHKA | |
| SCHEMBL22492207 | 0.79 | KDM5C (0.49) | ALDH1A1KDM4EKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647781-B2 | Redox fuel cells | ACAL ENERGY LIMITED (GB) | 2014-02-11 | — | — | US | disclosed |
| US-8647781-B2 | Redox fuel cells | ACAL ENERGY LIMITED (GB) | 2014-02-11 | — | — | US | disclosed |
| EP-2235781-B1 | REDOX FUEL CELLS | ACAL ENERGY LTD (GB) | 2012-10-24 | — | — | EP | disclosed |
| US-20110014532-A1 | REDOX FUEL CELLS | ACAL ENERGY LIMITED (GB) | 2011-01-20 | — | — | US | disclosed |
| US-20110014532-A1 | REDOX FUEL CELLS | ACAL ENERGY LIMITED (GB) | 2011-01-20 | — | — | US | disclosed |
| WO-2009093082-A1 | REDOX FUEL CELLS | ACAL ENERGY LIMITED (GB) | 2009-07-30 | — | — | WO | disclosed |