SCHEMBL129134

SCHEMBL129134

COC(=O)CC(=O)OCOC(=O)CC(=O)OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.55
GAA P10253 2/20 0.55
SI P14410 2/20 0.55
MGAM2 Q2M2H8 2/20 0.55
TSHR P16473 4/20 0.53
HSD17B10 Q99714 2/20 0.48
KMT2A Q03164 2/20 0.39
TET2 Q6N021 1/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.38
LMNA P02545 2/20 0.37
CA12 O43570 1/20 0.37
CA14 Q9ULX7 1/20 0.37
KDM4E B2RXH2 1/20 0.37
RECQL P46063 1/20 0.37
ALDH1A1 P00352 4/20 0.37
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
HSP90AB1 P08238 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17167768 0.89 GAA (0.75) MGAMGAASIMGAM2TSHR
SCHEMBL13141063 0.88 MGAM (0.50) MGAMGAASIMGAM2TSHR
SCHEMBL3441102 0.87 MGAM (0.69) MGAMGAASIMGAM2TSHR
SCHEMBL53913 0.87
SCHEMBL14375215 0.85 MGAM (0.52) MGAMGAASIMGAM2TSHR
SCHEMBL18736735 0.83 GAA (0.41) MGAMGAASIMGAM2TSHR
SCHEMBL4776595 0.83 MGAM (0.65) MGAMGAASIMGAM2TSHR
Hydrochloric Acid SCHEMBL5097295 0.83 MGAM (0.65) MGAMGAASIMGAM2TSHR
SCHEMBL708003 0.83 MGAM (0.65) MGAMGAASIMGAM2TSHR
Lithium SCHEMBL11306430 0.83 MGAM (0.65) MGAMGAASIMGAM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9771458-B2 Reactive functional siloxane compositions MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2017-09-26 US disclosed
US-20170129837-A1 VINYLBENZYLATED PHENOL COMPOUND, METHOD OF MANUFACTURING VINYLBENZYLATED PHENOL COMPOUND, ACTIVATED ESTER RESIN, METHOD OF MANUFACTURING ACTIVATED ESTER RESIN, THERMOSET RESIN COMPOSITION, HARDENED MATERIAL OF THERMOSET RESIN COMPOSITION, INTERLAYER INSULATING MATERIAL, PREPREG, AND METHOD OF MANUFACTURING PREPREG AIR WATER INC. (JP) 2017-05-11 US disclosed
US-20160251483-A1 Reactive Functional Siloxane Compositions MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2016-09-01 US disclosed
US-8703264-B2 Optical disc DIC CORPORATION (JP) 2014-04-22 US disclosed
US-20120099412-A1 ULTRAVIOLET CURABLE COMPOSITION FOR OPTICAL DISC AND OPTICAL DISC DIC CORPORATION (JP) 2012-04-26 US disclosed
US-20120060175-A1 OPTICAL DISC DIC CORPORATION (JP) 2012-03-08 US disclosed
US-20110033650-A1 ULTRAVIOLET-CURABLE COMPOSITION FOR LIGHT-TRANSMISSION LAYER AND OPTICAL DISK DIC CORPORATION (JP) 2011-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170129837-A1 VINYLBENZYLATED PHENOL COMPOUND, METHOD OF MANUFACTURING VINYLBENZYLATED PHENOL COMPOUND, ACTIVATED ESTER RESIN, METHOD OF MANUFACTURING ACTIVATED ESTER RESIN, THERMOSET RESIN COMPOSITION, HARDENED MATERIAL OF THERMOSET RESIN COMPOSITION, INTERLAYER INSULATING MATERIAL, PREPREG, AND METHOD OF MANUFACTURING PREPREG PARP10, VMA21, EP300 MGAM 2483/4885GAA 3177/4885SI 2686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.