Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 2/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BTN3A1 | O00481 | 5/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ENO1 | P06733 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4482845 | 0.93 | GAA (0.46) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL15635179 | 0.85 | TSHR (0.54) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL681950 | 0.83 | PRKCA (0.46) | GAAPRKCABTN3A1ALDH1A1POLB | |
| SCHEMBL129134 | 0.83 | MGAM (0.55) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL4482847 | 0.83 | PRKCA (0.37) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL3836339 | 0.82 | TSHR (0.52) | TSHRPRKCAALDH1A1RECQL | |
| SCHEMBL23306659 | 0.81 | MGAM (0.33) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL3835787 | 0.80 | TSHR (0.50) | GAATSHRPRKCAALDH1A1RECQL | |
| SCHEMBL3829281 | 0.80 | TSHR (0.50) | GAATSHRPRKCAALDH1A1RECQL | |
| SCHEMBL3838294 | 0.80 | TSHR (0.50) | GAATSHRPRKCAALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060418-A1 | PROTECTED CARBOXYLIC ACID-BASED METABOLITES FOR THE TREATMENT OF MITOCHONDRIA-RELATED DISEASES | NEUROVIVE PHARMACEUTICAL AB (SE) | 2017-04-13 | — | — | WO | disclosed |