Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12913708 | 0.88 | VDR (0.73) | VDRKDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL12913703 | 0.85 | VDR (0.44) | VDRKDM4EMAPTGAAKMT2A | |
| SCHEMBL31079393 | 0.83 | VDR (0.57) | VDRKDM4EMAPTGAAKMT2A | |
| SCHEMBL31079361 | 0.81 | VDR (0.55) | VDRKDM4EMAPTGAAHPGD | |
| SCHEMBL14478835 | 0.80 | VDR (0.59) | VDRKDM4EMAPTGAAKMT2A | |
| SCHEMBL12913695 | 0.78 | GAA (0.49) | VDRKDM4EMAPTGAAKMT2A | |
| SCHEMBL15358726 | 0.76 | VDR (0.53) | VDRKDM4EMAPTGAAHSD17B10 | |
| SCHEMBL12913707 | 0.76 | VDR (0.56) | VDRKDM4EMAPTHSD17B10LMNA | |
| SCHEMBL13901949 | 0.73 | KDM4E (1.00) | VDRKDM4EMAPTGAAHPGD | |
| SCHEMBL12913699 | 0.72 | GAA (0.45) | VDRKDM4EMAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872079-B2 | Naphthoxazine composition | SEKISUI CHEMICAL CO., LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-7872079-B2 | Naphthoxazine composition | SEKISUI CHEMICAL CO., LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090240006-A1 | A curable mixture of a naphthazine compound having a terminal aromatic ring bearing an hydroxyl group and a epoxy resins; high heat resistance; hardness; tensile strength;mechanical strength; dimensional stability; moldings; electronics; spacecraft; aircraft;automobile parts | CASE WESTERN RESERVE UNIVERSITY (US) | 2009-09-24 | — | — | US | disclosed |
| US-20090240006-A1 | A curable mixture of a naphthazine compound having a terminal aromatic ring bearing an hydroxyl group and a epoxy resins; high heat resistance; hardness; tensile strength;mechanical strength; dimensional stability; moldings; electronics; spacecraft; aircraft;automobile parts | CASE WESTERN RESERVE UNIVERSITY (US) | 2009-09-24 | — | — | US | disclosed |