Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12913695 | 0.88 | GAA (0.49) | GAAMEN1KMT2AMAPTLMNA | |
| SCHEMBL12913702 | 0.82 | MEN1 (0.49) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12913709 | 0.81 | VDR (0.43) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12913698 | 0.77 | MEN1 (0.52) | GAAMEN1KMT2AHSD17B10VDR | |
| SCHEMBL12913705 | 0.76 | VDR (0.45) | GAAMEN1KMT2AMAPTLMNA | |
| SCHEMBL21160440 | 0.76 | VDR (0.38) | GAAMEN1KMT2AMAPTUSP2 | |
| SCHEMBL15892650 | 0.75 | CYP1A2 (0.38) | MAPTALDH1A1VDRL3MBTL1CYP1A2 | |
| SCHEMBL15892645 | 0.73 | CYP1A2 (0.44) | MAPTUSP2ALDH1A1HTTHSD17B10 | |
| SCHEMBL12913706 | 0.73 | CYP1A2 (0.55) | GAAMEN1KMT2AMAPTLMNA | |
| SCHEMBL12913697 | 0.72 | VDR (0.63) | GAAMEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872079-B2 | Naphthoxazine composition | SEKISUI CHEMICAL CO., LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-7872079-B2 | Naphthoxazine composition | SEKISUI CHEMICAL CO., LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090240006-A1 | A curable mixture of a naphthazine compound having a terminal aromatic ring bearing an hydroxyl group and a epoxy resins; high heat resistance; hardness; tensile strength;mechanical strength; dimensional stability; moldings; electronics; spacecraft; aircraft;automobile parts | CASE WESTERN RESERVE UNIVERSITY (US) | 2009-09-24 | — | — | US | disclosed |
| US-20090240006-A1 | A curable mixture of a naphthazine compound having a terminal aromatic ring bearing an hydroxyl group and a epoxy resins; high heat resistance; hardness; tensile strength;mechanical strength; dimensional stability; moldings; electronics; spacecraft; aircraft;automobile parts | CASE WESTERN RESERVE UNIVERSITY (US) | 2009-09-24 | — | — | US | disclosed |