SCHEMBL129182

SCHEMBL129182

O=C(O)c1cccc(CO)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.68
SMN1; SMN2 Q16637 2/20 0.60
NPC1 O15118 1/20 0.60
TP53 P04637 1/20 0.60
MAPT P10636 1/20 0.60
XBP1 P17861 1/20 0.60
HTT P42858 1/20 0.60
RAB9A P51151 1/20 0.60
HSD17B10 Q99714 1/20 0.60
PRSS1 P07477 1/20 0.57
PRSS2 P07478 1/20 0.57
PRSS3 P35030 1/20 0.57
TSHR P16473 1/20 0.56
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
HIF1A Q16665 1/20 0.54
ANPEP P15144 1/20 0.54
ENPEP Q07075 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL7811295 0.98 FOLH1 (0.66) FOLH1SMN1; SMN2NPC1TP53MAPT
SCHEMBL27705266 0.92 FOLH1 (0.59) FOLH1SMN1; SMN2NPC1TP53MAPT
Benzoic Acid SCHEMBL5085787 0.89 TSHR (0.58) FOLH1SMN1; SMN2NPC1TP53MAPT
Isophthalic Acid SCHEMBL7568507 0.89 FOLH1 (0.60) FOLH1SMN1; SMN2NPC1TP53MAPT
SCHEMBL5519447 0.88 KMO (0.63) FOLH1NR4A2
Ether SCHEMBL7811293 0.88 MRGPRX4 (0.57) FOLH1SMN1; SMN2NPC1TP53MAPT
SCHEMBL27705270 0.87 FOLH1 (0.58) FOLH1SMN1; SMN2NPC1TP53MAPT
SCHEMBL29192780 0.85 FOLH1 (0.51) FOLH1SMN1; SMN2NPC1TP53MAPT
SCHEMBL30791058 0.84 FOLH1 (0.70) FOLH1PRSS1PRSS2PRSS3CYP2D6
SCHEMBL371526 0.84 FOLH1 (0.70) FOLH1CYP2D6CYP2C9HIF1AANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 617 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843276-B Multi-component composite steel slag grinding-aid excitant and preparation method thereof 华新水泥股份有限公司 2024-11-26 CN claimed
CN-118344284-A Compound with benzamide structure and preparation method and application thereof 杭州医学院 2024-07-16 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-117843276-A Multi-component composite steel slag grinding-aid excitant and preparation method thereof 华新水泥股份有限公司 2024-04-09 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-116675459-A Preparation method of cementing material reinforcing agent with high compressive strength 泉州市富霸新型材料科技发展有限公司 2023-09-01 CN claimed
CN-116345509-A Preparation method of 3-hydroxy-n-halogenated methyl benzoate compound 西安交通大学 2023-06-27 CN claimed
CN-115656353-A Method for detecting chemical components in peony flowers by UPLC-LTQ-Orbitrap-MS method 宿州学院 2023-01-31 CN claimed
CN-114315728-A Imidazole ionic liquid and application thereof in alcoholysis polymerization of 2, 5-furandicarboxylic acid ester 中国科学院大连化学物理研究所 2022-04-12 CN claimed
CN-114149391-A Method for alcoholysis polymerization of 2, 5-furan diformate 中国科学院大连化学物理研究所 2022-03-08 CN claimed
EP-1115693-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY Monsanto Company (US) 2001-07-18 EP claimed
EP-1091922-A1 METHOD OF PURIFYING AROMATIC DICARBOXYLIC ACIDS EASTMAN CHEMICAL COMPANY (US) 2001-04-18 EP claimed
EP-1019046-A1 PROTEASE INHIBITORS Smithkline Beecham (US) 2000-07-19 EP claimed
WO-2000018721-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
WO-2000000457-A1 METHOD OF PURIFYING AROMATIC DICARBOXYLIC ACIDS EASTMAN CHEMICAL COMPANY (US) 2000-01-06 WO claimed
WO-1998048799-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1998-11-05 WO claimed
US-5480761-A CHROMOGENIC PHOTOGRAPHIC ELEMENTS WITH DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1996-01-02 US claimed
WO-1992007830-A2 OXINDOLE PEPTIDE ANTAGONISTS PFIZER INC. (US) 1992-05-14 WO claimed
US-4528361-A Copolymers of hydroxymethylbenzoic acid and lactam STANDARD OIL COMPANY (INDIANA) (US) 1985-07-09 US claimed
US-4220753-A Alkyl alkoxymethylbenzoates STANDARD OIL COMPANY (INDIANA) (US) 1980-09-02 US claimed